Established in the year 1845, St Mary's Hospital became operational in the year 1851. It is one of the last voluntary health centers to have been set up. Till the year 1998, St Mary's Hospital administered the St Mary's Hospital Medical School of the University of London. Post 1998, it collaborated with Imperial College London, and later with Charing Cross and Westminster Medical School. Nobel Prize winner Alexander Fleming, noted for its penicillin discovery has been an alumni of St Mary's Hospital. Also, fourth in line to the throne, Prince Harry, was born here in the year 1984.