Born to musician parents Denis Matsuev proved to be a music prodigy at the age of three when he correctly replicated a tune having only heard it once. he began classical training under his father. He won a competition at the age of fifteen and earned the chance to study at the Moscow Conservatory. He has participated in various prestigious competitions and placed well. Matsuev has worked alongside several famed ensembles and orchestras. He has been lauded for his performances.